MicroRNAs and the cellular response to rapamycin
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چکیده
منابع مشابه
MicroRNAs and the cellular response to rapamycin
The mammalian target of rapamycin (mTOR) is a major regulator of cell growth, motility and angiogenesis that is often deregulated in malignancies. mTOR inhibitors have been approved for the treatment of renal cell carcinoma and mantle cell lymphoma. Currently, secondgeneration mTOR inhibitors are under clinical evaluation. Major challenges remain in the identification of patients who will respo...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2013
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.24100